What causes neurovasculitis?

Neurovasculitis may be caused by genetics, external environmental factors, autoimmune dysfunction or other diseases. The cause must be identified as soon as possible, and targeted treatment measures must be taken according to the specific situation to avoid worsening of the disease.

1) Genetic factors

Genetics may make some people more susceptible to neurovasculitis. If there is a family history of related diseases, the risk of this disease may increase. At the same time, certain immune diseases that are associated with heredity (such as systemic lupus erythematosus, rheumatoid arthritis, etc.) may also induce neurovasculitis. If genetic factors are suspected to be related, a family history survey should be conducted in a timely manner and further confirmed through genetic testing.

2) Environmental factors

External viral and bacterial infections may cause neurovasculitis. Some infections can stimulate the immune system, making it abnormally active and attacking healthy vascular tissue. Long-term contact or improper use of certain chemicals and drugs (such as anti-infective drugs) may also induce the disease. In this case, you should avoid contact with possible environmental pathogens and check relevant indicators regularly.

3) Abnormal autoimmune function

Neurovasculitis is mostly an autoimmune-related disease. When the immune system mistakenly identifies its own tissue as an "enemy", it may cause inflammation of the blood vessel wall, which in turn causes neurological symptoms. Certain immune system disorders, such as multiple sclerosis and Sjögren's syndrome, may also cause vasculitis. If immune abnormalities are confirmed, doctors usually use glucocorticoids (such as prednisone) and immunosuppressants (such as cyclophosphamide or methotrexate) to control the condition.

4) Other diseases

Neurovasculitis may also be secondary to other diseases, such as systemic diseases (such as malignant tumors, viral hepatitis, etc.). These diseases may trigger systemic inflammatory responses and affect the neurovascular system. Only by improving viral antibody analysis and imaging examinations can we accurately determine whether it is a secondary condition. During treatment, the primary disease must be treated at the same time.

5) Pathological mechanism (neurovascular disease)

The pathological mechanism of neurovasculitis is that the blood vessel wall of the local nerve is damaged, resulting in abnormal blood supply, causing nerve pain, numbness or movement disorders. If it continues to be uncontrolled, it may even cause nerve necrosis. Professional examinations such as nerve conduction function tests or vascular biopsy can help to clarify the diagnosis, and surgical treatment (such as vascular bypass grafting) can be considered in severe patients.

If neurovasculitis is suspected or confirmed, it is recommended to go to the rheumatology and immunology department, neurology department and other departments of a regular hospital as soon as possible for detailed examination and standardized treatment to avoid delaying the progression of the disease and causing irreversible nerve damage. Patients with mild symptoms should pay attention to avoiding inducing factors and follow the doctor's advice for regular follow-up visits to ensure that the condition is stable.