What causes vasculitis?

Vasculitis can be caused by genetic, environmental, physiological, traumatic, and pathological factors, each in different ways. Once these factors are identified, targeted treatment strategies can be used, including medication, lifestyle modifications, and possibly surgical intervention.

1. Genetic factors: Some types of vasculitis are thought to be related to inherited genes, especially when there is a history of similar diseases in the family. Although not all types of vasculitis have a clear genetic tendency, genetic susceptibility may increase an individual's risk of disease in some cases. Genetic testing and family history investigation can help identify genetic risks.

2. Environmental factors: External factors such as pollution, infection, and drugs may be the cause of vasculitis. Infections include bacteria and viruses, which may stimulate the body's immune response, leading to vasculitis. Avoiding infection sources, maintaining good hygiene habits, and vaccination are some ways to prevent it.

3. Physiological factors: Abnormalities in the individual's immune system are also one of the causes of vasculitis. Autoimmune disorders may cause the immune system to mistakenly attack the blood vessel wall, causing inflammation and damage. In this case, immunosuppressants (such as glucocorticoids, cyclophosphamide, immunoglobulins) may be used to slow down the immune response.

4. Trauma: Physical damage and trauma may cause local vascular inflammation. Treatment is often based on protecting the damaged area and combined with anti-inflammatory drugs.

5. Pathological factors: Certain systemic diseases (such as lupus erythematosus, rheumatoid arthritis) may increase the incidence of vasculitis. The management of these diseases requires systemic treatment to control the activity of the main disease.

Ultimately, treatment of vasculitis is individualized based on the specific cause, which is key to both managing symptoms and preventing complications. It is important to seek medical advice promptly for any symptoms that suggest vasculitis. With professional medical advice and a personalized treatment plan, you can effectively manage your condition and improve your quality of life. Maintaining a healthy lifestyle, regular health checks, and managing medications as directed by your doctor will help reduce the impact of vasculitis.