Six factors that cause gallstones

The formation of gallstones is mainly related to a variety of factors such as genetics, diet, lifestyle and body metabolism, including six key factors such as genetic predisposition, unhealthy diet, high cholesterol, obesity, metabolic disorders and chronic cholecystitis. Understanding these factors can help prevent and control the occurrence of gallstones.

1. Influence of genetic factors

People with a family history of gallstones are more likely to develop the disease. Studies have found that genes related to gallbladder metabolism may affect the composition of bile and cholesterol metabolism, thereby increasing the risk of gallstone formation. People with a family history of the disease are advised to undergo regular physical examinations, especially ultrasound examinations, for early detection.

2. Unhealthy eating habits

A high-fat, high-cholesterol diet increases the probability of gallstone formation. For example, frequent intake of high-fat foods such as fried foods, animal offal, and cream will increase the cholesterol level in bile and form crystal deposits. It is recommended to choose a low-fat diet and eat more foods rich in dietary fiber, such as green leafy vegetables, whole grains, and fruits, which can help lower cholesterol.

3. Overweight or obese

Obesity is one of the important causes of gallstone formation. Obese people have higher cholesterol levels, and the bile secreted by the liver is easily oversaturated, increasing the risk of gallstone formation. Controlling weight and avoiding rapid weight loss are the keys to preventing gallstones. It is recommended to do more than 30 minutes of aerobic exercise every day, such as brisk walking, swimming or yoga, and maintain a reasonable diet structure.

4. Metabolic disorders

Metabolic diseases such as diabetes or insulin resistance can affect the balance of bile acid secretion in the liver, leading to an imbalance in the proportion of bile components and the formation of gallstones. Controlling blood sugar and improving insulin sensitivity are measures to prevent gallstones, and a balanced diet and moderate exercise can help restore metabolism.

5. Chronic gallbladder inflammation

Chronic cholecystitis can lead to impaired gallbladder concentration function, poor bile flow, and the development of gallstones. Patients often experience symptoms such as right upper abdominal pain and nausea. It is recommended that such patients seek medical attention as soon as possible and choose antibiotic treatment or surgical removal of the gallbladder according to their condition to avoid worsening of the condition.

6. Special physiological state

Pregnant women are also at high risk of gallstones due to increased progesterone secretion, which can lead to decreased gallbladder contraction and bile retention. In addition, women of advanced age and those taking estrogen therapy are also at high risk. It is recommended to pay attention to pregnancy care, regularly check gallbladder health, and reduce the intake of high-cholesterol foods in the diet.

Understanding the formation mechanism and risk factors of gallstones can minimize the risk of developing them. Developing good eating and living habits, maintaining a healthy weight, and detecting physical discomfort early are important measures to prevent gallstones. If related symptoms occur, you should see a doctor as soon as possible to avoid delaying treatment.