Iga vasculitis and Henoch-Schonlein purpura

The treatment of IgA vasculitis and Henoch-Schönlein purpura requires the selection of drugs or supportive treatments according to the severity of the disease. Both are related to abnormalities of the immune system. IgA vasculitis is a vascular inflammation characterized by the deposition of IgA immune complexes, while Henoch-Schönlein purpura is a vasculitis characterized by skin purpura, joint pain, abdominal pain and kidney damage.

1. Treatment of IgA vasculitis includes glucocorticoids, immunosuppressants and biologics. Glucocorticoids such as prednisone can effectively control inflammation, immunosuppressants such as cyclophosphamide and azathioprine are used for severe patients, and biologics such as rituximab are suitable for refractory cases. The treatment of allergic purpura is mainly symptomatic. Mild patients can use antihistamines such as loratadine, severe patients need to use glucocorticoids such as prednisone, and patients with kidney damage need to use immunosuppressants such as cyclosporine.

2. The etiology of IgA vasculitis involves genetic, environmental and immune factors. Genetic factors include HLA gene polymorphism, environmental factors such as infection and drugs can induce the disease, and immune factors such as IgA immune complex deposition lead to vascular inflammation. The etiology of Henoch-Schönlein purpura is related to infection, drug and food allergy, such as streptococcal infection, drug such as antibiotics, and food allergy such as seafood and nuts.

3. Prevention of IgA vasculitis includes avoiding infection, using medications properly and having regular physical examinations. Avoid infection, such as washing hands frequently and wearing masks, use medications properly, such as using antibiotics as prescribed by doctors, and have regular physical examinations, such as monitoring kidney function. Prevention of Henoch-Schonlein purpura includes avoiding allergens, enhancing immunity and eating a healthy diet. Avoid allergens, such as staying away from known allergic foods, enhance immunity, such as exercising moderately, and eat a healthy diet, such as eating more fruits and vegetables.

The treatment and prevention of IgA vasculitis and Henoch-Schönlein purpura require comprehensive consideration of the cause and condition. Timely medical treatment and standardized treatment are the key. Patients should take medication as prescribed by the doctor and have regular check-ups. Maintaining good living habits and a healthy diet will help control the disease.