Causes of aneurysms caused by vascular malformations

The main reason for vascular malformations to cause aneurysms is abnormal vascular wall structure, which causes local vascular dilation and aneurysm formation. Vascular malformations may be caused by genetic factors, environmental stimulation, physiological changes or pathological conditions. Treatment methods include drug therapy, surgical treatment and lifestyle adjustments.

1. Genetic factors are an important cause of vascular malformations. Certain gene mutations may lead to abnormal development of blood vessel walls and increase the risk of aneurysms. People with a family history of vascular malformations or aneurysms need regular checkups to detect potential problems early.

2. Environmental factors such as long-term high blood pressure, smoking and alcohol abuse can aggravate the damage to the blood vessel wall. High blood pressure puts greater pressure on the blood vessels, which may cause the expansion of weak parts of the blood vessel wall under long-term effects. Quitting smoking, limiting alcohol consumption and controlling blood pressure are important measures to prevent aneurysms.

3. Physiological changes such as aging and hormone fluctuations can also affect blood vessel health. As we age, blood vessels become less elastic and more prone to deformities. When women's hormone levels change during menopause, their blood vessel walls may become more fragile.

4. Trauma or infection may cause direct damage to the blood vessel wall, increasing the risk of aneurysm formation. Severe head or neck trauma may cause vascular malformations, and certain infectious diseases may also cause vascular inflammation, which may then develop into an aneurysm.

5. Pathological conditions such as atherosclerosis and connective tissue diseases may also cause vascular malformations. Atherosclerosis causes the blood vessel wall to thicken and lose elasticity, while connective tissue diseases may affect the structural integrity of the blood vessel wall.

Treatments include medication, surgery, and lifestyle adjustments. Medication can include antihypertensive drugs such as amlodipine, beta-blockers such as metoprolol, and lipid-lowering drugs such as atorvastatin. Surgical treatments include intravascular embolization, craniotomy clipping, and vascular stent implantation. Lifestyle adjustments recommend a low-salt, low-fat diet, moderate exercise such as walking or swimming, and regular monitoring of blood pressure and blood lipids.

The causes of aneurysms caused by vascular malformations are complex, involving genetic, environmental, physiological and pathological factors. Early detection and comprehensive treatment measures are the key to preventing and controlling aneurysms.