What causes ventricular septal defect in infants?

How is ventricular septal defect caused in infants?

Ventricular septal defect is the most common congenital heart disease. Ventricular septal defect in infants will have a certain impact on heart function, respiratory function and growth and development of children. It is best to prevent the cause during pregnancy.

It is generally believed that the causes of ventricular septal defects in infants are as follows:

1. Family inheritance: It is common for parents and children to have ventricular septal defects. If the first child has a ventricular septal defect, the probability of the second child is 2%; if both children have ventricular septal defects, the probability of the next child will increase to 10%. When the mother has a ventricular septal defect, the probability of the child suffering from a ventricular septal defect is 10%.

2. Pregnant women do not control diabetes: If a pregnant woman has diabetes, if it is not effectively controlled, it will lead to 2% of fetal congenital heart disease. Controlling diabetes in early pregnancy can reduce the risk of ventricular septal defect in children.

3. Pregnant women’s exposure to teratogenic drugs: When pregnant women are exposed to teratogenic drugs such as lithium, phenytoin sodium, steroids, etc. in the early stages of pregnancy, the incidence of congenital heart disease in the fetus can be as high as 2%.

4. Pregnant women are exposed to excessive radiation: Excessive radiation in early pregnancy: Excessive radiation in early pregnancy: Excessive radiation from radioactive substances such as X-rays and isotopes.

5. Pregnant women are infected with viruses: If pregnant women are infected with viruses in the first three months of pregnancy, especially during the 3-8 weeks of pregnancy, it may cause fetal ventricular septal defect. Rubella virus is an important cause of fetal ventricular septal defect.

6. Consanguineous marriage: Consanguineous marriage is a risk factor for fetal malformation and ventricular septal defect.

7. Bad habits: "Smoking" during pregnancy, husband smoking, and wife "passive smoking" can all lead to fetal malformation or ventricular septal defects. Among newborns with ventricular septal defects, babies born to smoking mothers are twice as likely as non-smokers. Sleeping in the same bed can lead to fetal chromosomal abnormalities, neonatal alcohol poisoning, and more cardiovascular malformations.